ProtoTOX is a computational application for the prediction of toxicological properties of chemical compounds, by using proprietary QSAR models.
QSAR models in ProtoTOX
REACH code: 8.1.1
REACH code: 8.2.2
REACH code: 8.3
Mutagenicity (Ames test)
REACH code: 8.4.1
REACH code: 8.4.2
REACH code: 8.4.3
REACH code: 8.5.1
REACH code: 8.7.2
REACH code: 8.9.1
ProtoTOX is a module focused on the prediction of endpoints related with the toxicity of
chemical substances. It includes a variety of in vitro and in vivo tests in
humans, animals, microorganisms and cell lines.
ProtoTOX mainly includes, but is not limited to, endpoints used by
REACH, a European Union regulation, adopted to improve the protection of human health and the environment from the risks that can be posed by chemicals, while enhancing the competitiveness of the EU chemicals industry.
REACH also promotes alternative methods for the hazard assessment of substances in order to reduce the number of tests on animals. The requirements for registering a chemical substance are organized as annexes of the REACH regulation. Different
annexes must be used depending on the substance mass produced or imported by each company.